| Day | Date | Opponent | Location | Outcome/Time |
| Thu | 02/24/2000 | Air Force^ | Millington, TN | W, 6-0
Recap | Stats | Archived Audio |
| Fri | 02/25/2000 | Ohio State^ | Millington, TN | L, 5-4
Recap | Stats | Archived Audio |
| Sun | 02/27/2000 | Memphis | Millington, Tenn. | W, 4-3
Recap | Stats | Archived Audio |
| Fri | 03/03/2000 | Wake Forest | Minneapolis, Minn.
(Hormel Foods Classic) | W, 8-5
Recap | Stats | Archived Audio |
| Sat | 03/04/2000 | Minnesota+ | Minneapolis
(MN) Metrodome | L, 9-7
Recap | Stats | Archived Audio |
| Sun | 03/05/2000 | Georgia+ | Minneapolis
(MN) Metrodome | W, 6-4
Recap | Stats | Archived Audio |
| Tue | 03/07/2000 | Manchester College | Frank Eck Stadium | W, 5-1
Recap | Stats | No Audio Avail. |
| Sat | 03/11/2000 | Central Michigan# | Jacksonville, FL
(Harmon Stadium) | W, 5-0
Recap | Stats | Archived Audio |
| Sat | 03/11/2000 | Duquesne# | Jacksonville, FL
(Harmon Stadium) | W, 5-1
Recap | Stats | Archived Audio |
| Sun | 03/12/2000 | Illinois | Jacksonville, Fla.
(at UNF) | W, 5-1
Recap | Stats | Archived Audio |
| Mon | 03/13/2000 | North Florida# | Jacksonville, FL
(at UNF) | L, 6-1
Recap | Stats | Archived Audio |
| Wed | 03/15/2000 | Butler# | Jacksonville, FL
(at UNF) | W, 3-2
Recap | Archived Audio |
| Thu | 03/16/2000 | Iowa# | Jacksonville, FL
(at UNF) | W, 3-2
Recap | Stats |
| Fri | 03/17/2000 | Akron# | Jacksonville, FL
(at UNF) | W, 10-3
Recap | Stats |
| Sat | 03/18/2000 | Illinois | Jacksonville, Fla.
(at UNF) | W, 12-3
Recap | Stats |
| Wed | 03/22/2000 | Detroit | Frank Eck Stadium | W, 10-3
Recap | Stats | Archived Audio |
| Sat | 03/25/2000 | Villanova* | Villanova, PA | W, 4-0
Recap | Stats |
| Sat | 03/25/2000 | Villanova | Villanova, Pa. | W, 7-3, 10 inn.
Recap | Stats |
| Sun | 03/26/2000 | Villanova* | Philadelphia, PA | L, 11-5
Recap | Stats |
| Wed | 03/29/2000 | Wisconsin-Milwaukee | Frank Eck Stadium | L, 14-3
Recap | Stats | Archived Audio |
| Thu | 03/30/2000 | Siena | Frank Eck Stadium | W, 9-2
Recap | Stats | No Audio Avail. |
| Sat | 04/01/2000 | Connecticut* (2) | Storrs, CT | W, 8-3, L 8-1
Recap | Stats | Game 2 Stats | Archived Audio |
| Sun | 04/02/2000 | Connecticut* | Storrs, CT | W, 9-2
Recap | Stats | Archived Audio |
| Wed | 04/05/2000 | Valparaiso | Frank Eck Stadium | W, 7-2
Recap | Stats | Archived Audio |
| Thu | 04/06/2000 | IUPUI | Frank Eck Stadium | W, 7-3
Recap | Stats | Archived Audio |
| Sat | 04/08/2000 | Boston College | Frank Eck Stadium | W, 12-1
Recap | Stats | Archived Audio |
| Sun | 04/09/2000 | Boston College* | Frank Eck Stadium | W, 10-6
Recap | Stats | Archived Audio |
| Sun | 04/09/2000 | Boston College* | Frank Eck Stadium | L, 11-1
Recap | Stats |
| Tue | 04/11/2000 | Purdue | Frank Eck Stadium | L, 7-5
Recap | Stats | Archived Audio |
| Wed | 04/12/2000 | Bowling Green | Frank Eck Stadium | W, 2-1
Recap | Stats | Archived Audio |
| Thu | 04/13/2000 | Toledo | Frank Eck Stadium | W, 6-3
Recap | Stats | Archived Audio |
| Sat | 04/15/2000 | West Virginia* | Morgantown, WV | W, 3-1 (10)
Recap | Stats | Archived Audio |
| Sat | 04/15/2000 | West Virginia * | Morgantown, WV | L, 7-2
Recap | Stats |
| Sun | 04/16/2000 | West Virginia* | Morgantown, WV | W, 4-3
Recap | Stats | Archived Audio |
| Tue | 04/18/2000 | Chicago State | Frank Eck Stadium | W, 12-2
Recap | Stats | Archived Audio |
| Tue | 04/18/2000 | Chicago State | Frank Eck Stadium | W, 4-1
Recap | Stats |
| Thu | 04/20/2000 | Seton Hall* (2) | South Orange, NJ | W, 11-5, 5-1
Recap | Stats |
| Sat | 04/22/2000 | Georgetown* | Washington D.C. | W, 5-1
Recap | Stats |
| Sat | 04/22/2000 | Georgetown* | Washington, D.C. | W, 12-1
Recap | Stats |
| Tue | 04/25/2000 | Western Michigan | Kalamazoo, MI | L, 11-7
Recap | Stats | Archived Audio |
| Wed | 04/26/2000 | Michigan | Comstock Park, MI | W, 5-4 (11)
Recap | Stats | Archived Audio |
| Thu | 04/27/2000 | Cleveland State | Frank Eck Stadium | W, 9-6
Recap | Live Audio |
| Sat | 04/29/2000 | St. John's* (2) | Frank Eck Stadium | W, 8-3
Recap | Stats | Archived Audio |
| Sat | 04/29/2000 | St. John's | Frank Eck Stadium | L, 6-4
Recap | Stats |
| Sun | 04/30/2000 | St. John's* | Frank Eck Stadium | W, 9-8
Recap | Archived Audio |
| Tue | 05/02/2000 | Northwestern | Frank Eck Stadium | L, 9-4
Recap | Stats | Archived Audio |
| Wed | 05/03/2000 | Oakland (MI) | Frank Eck Stadium | W, 9-3
Recap | Stats | Archived Audio |
| Wed | 05/03/2000 | Oakland (MI) | Frank Eck Stadium | W, 5-3
Recap | Stats |
| Sat | 05/06/2000 | Pittsburgh* (2) | Frank Eck Stadium | W, 7-0
Recap | Stats | Archived Audio |
| Sat | 05/06/2000 | Pittsburgh | Frank Eck Stadium | W, 11-8
Recap | Stats | Archived Audio |
| Sun | 05/07/2000 | Pittsburgh* | Frank Eck Stadium | L, 22-18
Recap | Stats | Archived Audio |
| Sat | 05/13/2000 | Rutgers* (2) | Frank Eck Stadium | L, 16-6
Recap | Stats | Archived Audio |
| Sat | 05/13/2000 | Rutgers | Frank Eck Stadium | W, 4-3
Recap | Stats |
| Sun | 05/14/2000 | Rutgers* | Frank Eck Stadium | W, 10-6
Recap | Stats | Archived Audio |
| Wed | 05/17/2000 | Boston College (BIG EAST Tournament) | Bridgewater, NJ | L, 4-3
Recap | Stats | Archived Audio |
| Thu | 05/18/2000 | Pittsburgh (BIG EAST Tournament) | Bridgewater, NJ | W, 15-7
Recap | Stats |
| Fri | 05/19/2000 | Boston College (BIG EAST Tournament) | Bridgewater, NJ | L, 6-5
Recap | Stats | Archived Audio |
| Fri | 05/26/2000 | Tulane | Starkvill, Miss.
(NCAA Regional) | W, 8-4
Recap | Stats | Archived Audio |
| Sat | 05/27/2000 | Mississippi State | Starkville, Miss.
(NCAA Regional) | L, 8-1
Recap | Stats | Archived Audio |
| Sat | 05/27/2000 | Tulane | Starkville, Miss.
(NCAA Regional) | W, 10-6
Recap | Stats |
| Sun | 05/28/2000 | Mississippi State | Starkville, Miss.
(NCAA Regional) | W, 7-0
Recap | Stats | Archived Audio |
| Sun | 05/28/2000 | Mississippi State | Starkville, Miss.
(NCAA Regional) | L, 10-9
Recap | Stats | Archived Audio |
