The Irish will compete against Denver, Minnesota and Nebraska.
Notre Dame sports two individuals in the final eight of the singles draw and two teams in the final eight of the doubles draw.
The Irish look to move one step closer to title on Saturday.
The two will battle foes from Illinois State and DePaul, respectively, for a spot in the singles draw.
Notre Dame set to compete against some of region's best.
Images of the Irish during another successful campaign.
Men's Tennis played in the first day of the Tom Fallon Invitational at the Courtney Tennis Center on September 23rd.